Pyrazinyl-Substituted Aminoazoles as Covalent Inhibitors of Thrombin: Synthesis, Structure, and Anticoagulant Properties
Imberg, L.; Siutkina, A. I.; Erbacher, C.; Schmidt, J.; Broekmans, D. F.; Ovsepyan, R. A.; Daniliuc, C. G.; Gonçalves de Oliveira, E.; Serafim, M. S. M.; O’Donoghue, A. J.; Pillaiyar, T.; Panteleev, M. A.; Poso, A.; Kalinina, S. A.; Bermúdez, M.; Nekipelov, K.; Bendas, G.; Karst, U.; Kalinin, D. V.*
ACS Pharmacology & Translational Science, 8, 2025, 146-172. DOI: 10.1021/acsptsci.4c00515
Total synthesis of (±)-auranthine confirmed its refined structure.
Reinker, M.; Kalinina, S. A.; Kalinin, D. V.*
RSC Advances, 2024, 14(3), 1649-1654. DOI: DOI: https://doi.org/10.1039/D3RA07483H
Functional-Group-Tolerant Pd-Catalyzed Carbonylative Negishi Coupling with Aryl Iodides
Kalinin, D.V.; Ulven T.
ACS J. Org. Chem. 2023, 88, 23, 16633–16638. DOI: https://doi.org/10.1021/acs.joc.3c00948
Amide-functionalized 1,2,4-Triazol-5-amines as Covalent Inhibitors of Blood Coagulation Factor XIIa and Thrombin.
Imberg, L.; Platte, S.; Erbacher, C.; Daniliuc, C.G.; Kalinina, S.A.; Dörner, W.; Poso, A.; Karst, U.; Kalinin, D.V.*
ACS Pharmacology & Translational Science, 5, 2022, 1318-1347. DOI: https://doi.org/10.1021/acsptsci.2c00204
Microscale Parallel Synthesis of Acylated Aminotriazoles Enabling the Development of Factor XIIa and Thrombin Inhibitors.
Platte, S., Korff, M., Imberg, L., Balicioglu, I., Erbacher, C., Will, J.M., Daniliuc, C.G. and Karst, U., Kalinin, D.V.*
ChemMedChem 2021, 16, 3672 – 3690. DOI: https://doi.org/10.1002/cmdc.202100431
Acylated 1H-1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action.
Korff, M.; Imberg, L.; Will, J. M.; Buckreiss, N.; Kalinina, S. A.; Wenzel, B. M.; Kastner, G. A.; Daniliuc, C. G.; Barth, M.; Ovsepyan, R. A.; Butov, K. R.; Humpf, H. U.; Lehr, M.; Panteleev, M. A.; Poso, A.; Karst, U.; Steinmetzer, T.; Bendas, G.; Kalinin, D. V.*
J. Med. Chem. 2020, 63, 13159-13186. DOI: https://doi.org/10.1021/acs.jmedchem.0c01635
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